Iibka Kulul ee Shiinaha CAS 7361-61-7 Xylazine cannabinoids budada cad
Qaab dhismeedka kiimikada
La mid ah:
2- (2,6-dimethylanilino) -5,6-dihydro-4h-1,3-thiazine;
2- (2,6-dimethylphenylamino) -4h-5,6-dihydro-1,3-thiazine;
5,6-dihydro-2- (2,6-xylidino) -4h-1,3-thiazine;
5,6-dihydro-2- (2,6-xylidino) -4h-3-thiazine;
2- (2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine;
Xylazine Base & HCL;
Xylazine,2- (2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine hydrochloride;
Xylazine (200 mg)
Sharaxaada
Xylazine waa agonist of α2-adrenergic reseptors (Ki = 194 nM).Waa analoogga clonidine, α2-adrenergic agonist receptor loo isticmaalo si loo yareeyo cadaadiska dhiigga.Xylazine waxaa loo isticmaalaa suuxinta, suuxinta, iyo xanuunka xanuunka ee naasleyda aan bini-aadmiga ahayn.Alaabtan waxa kale oo loo heli karaa sidii halbeeg tixraaceedka falanqaynta .
Asalkiilaha Xylazine, Bayer
Adeegsada
Antinociceptive; Alpha-2 adrenergic agonist
Adeegsada
Xylazine waa fasalka α2 ee adrenergic agonist receptor.Xylazine waa analoque clonidine ah oo u shaqeysa presynaptic iyo reseptors postsynaptic sida 2-adrenergic agonist.
Habka wax-soo-saarka
2,6-Dimethylphenyl isothiocyanate, 31.0 g (0.2 mole), oo laga diyaariyey 2,6-dimethylaniline oo leh thiophosgene, ayaa lagu daray hoos u dhac inta lagu jiro 15 min si fiican loo walaaqay ee 15.0 g (0.2 mole) ee 3-aminopropanol-1 in 100 ml oo ah ether.Eter-kii ayaa bilaabay inuu karkariyo.Walaaqaya dib-u-kicinta ayaa la sii waday 30 daqiiqo, ka dibna ether-ka ayaa la damiyay.Hadhaaga waxaa lagu daaweeyay 100 ml oo ah hydrochloric acid oo la karkariyey hoostiisa 30 daqiiqo.Kadib qaboojinta, waxaa lagu qasi jiray biyo, laga sifeeyay wasakh ka nadiif ah, iyo saldhigga ayaa lagu soo dajiyay iyada oo lagu daray xalka sodium hydroxide ee xoogga leh.Marka dib-u-crystallized laga bilaabo benzene-ligroin, xarunta natiijada 2- (2,6-dimethyl-phenylamino) -4H-5,6-dihydro-1,3-thiazine, barta dhalaalka 140-142 ° C (soo saara 90% ee aragtida ).
Shaqada daawaynta
Xanuun-jileec, suuxdin
Sharaxaada Guud
Xylazine waxay ku milmi kartaa methanol (50 mg/ml), taasoo keenta xal cad oo aan midab lahayn.Waxa kale oo ay ku milmi kartaa HCl acid iyo chloroform.Xylazine waa mid aan lagu milmi karin biyaha iyo xalalka alkali.
Waxqabadyada Biochem/physiol
Xylazine marka lala isticmaalo ketamiin waxaa loo tixgeliyaa inay tahay suuxin xoog leh oo badbaado leh xayawaanka tijaabada ah.Waxaa la og yahay in ay sare u qaaddo sii daynta beerka ee gulukooska, taas oo ka sii daraysa hyperglycemia.
Habka wax-qabadka
Xylazine waxaa loo suuq geeyaa cusbada hydrochloride sida Rompun (100 mg/mL) iyo Anased (20 mg/mL) xalalka la isku duro ee maamulka xididada ee fardaha iyo eyda, siday u kala horreeyaan.Ficilada xylazine waxaa laga yaabaa in lagu beddelo maamulka yohimbine, alkaloid indolalkylamine, kaas oo xannibaya kuwa α2-adrenoreceptors ee ay kiciso xylazine.
Xogta Badbaadada
Sunta la nuugo, dariiqyada maqaarka hoostiisa, iyo xididdada dhiigga.Saamaynta nidaamka aadanaha: isbeddelka dhaqdhaqaaqa dhaqdhaqaaqa, hoos u dhaca cadaadiska dhiigga, miosis, dhumucdiisuna, heerka garaaca wadnaha oo yaraada, hurdo la'aan.Marka la kululeeyo si uu u burburo waxa ay sii deysaa qiiq aad u sun ah oo ah NOx iyo SOx
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