Dhexdhexaadinta daawada 99% budada nadiifka ah CAS 86386-73-4 Fluconazol
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Macluumaadka aasaasiga ah
Fluconazole-D4 waxay u muuqataa sida caddaan ilaa jaale-caddaan budo crystalline ah oo waxoogaa ur leh oo dhadhan qadhaadh leh.
Waxay si fudud ugu milmi kartaa glacial acetic acid, methanol ama ethanol, oo si dhib leh ugu milmay biyaha oo ku dhawaad aan lagu milmi karin etherka iyada oo barta dhalaalaysa ay tahay 137 ~ 141.6 ℃, ama barta dhalaalka oo ah 138 ~ 140 ℃ (oo laga soo qaatay ethyl acetate-hexane).
Isticmaalka
Alaabtaan waxaa iska leh fluorinated triazole dawada antifungal antifungal spectrum leh antifungal spectrum la mid ah ketoconazole laakiin waxqabadka antifungal ayaa ka sarreeya ketoconazole.
Nidaamkeeda ficilku waa iyada oo la xakameynayo qaybta muhiimka ah ee xuubka unugyada fangas, ergosterol biosynthesis enzyme, xannibaya isku-darka ergosterol iyo jebinta sharafta derbiga unugyada fangas, oo sii adkeynaya korriimadooda iyo tarankooda.
Badeecadu waxay leedahay firfircoonida antifungal awood leh oo ka dhan ah Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum iyo epidermophyton.
Guryaha Kiimikada
Fluconazole-D4 waa Mid Adag oo Cadaan ah
Wuxuu adeegsadaa Fluconazole Summadaysan (F421000).Loo isticmaalo sidii antifungal.
Waxay isticmaashaa anticholinergic
Isticmaalka Fluconazole-D4 waxaa loo isticmaalaa daawaynta caabuqyada fangas.
Waxay isticmaashaa wakiilka antifungal-balaadhan ee triazole.
Tilmaamaha
Fluconazole (Diflucan) ayaa laga yaabaa in si fiican loo nuugo waxaana suurtogal ah in ay ka yar tahay hepatotoxic marka loo eego ketoconazole, laakiin aad bay uga qaalisan tahay, tixgelin muhiim ah oo la siiyay dhererka loo baahan yahay ee daaweynta cudurrada fangas ee maqaarka.